DHT and Testosterone - Man's best friend or worst enemy?

Testosterone enters the prostate and is converted to an active intermediate (DHT) which stimulates growth, protein synthesis and prostaglandin release in the cell. The enzyme 5-alpha-reductase converts the testosterone to DHT (dihydrotestosterone).

A decrease in testosterone levels can throughout the balance resulting in increased intraprostatic concentrations of DHT.

Cadmium, from cigarette smoke and air pollution, can increase the activity of the enzyme 5-alpha-reductase. Zinc helps to remove the cadmium as well as inhibit the overactive enzyme.

As testosterone and DHT are required in several areas of the male body, clinical tests should be undertaken first before prescribing DHT blockers.

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